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Article Summary X To perform an enema at home, start by lubricating your anus and the enema nozzle with coconut oil. Enemas should not be used if there is an undiagnosed abdominal pain since the peristalsis of the bowel can cause an inflamed appendix to rupture. Fleet enemas come in multiple versions so be sure to get the one that just has normal saline in it. How deeply you need to clean depends on how far ahead of time you're doing the cleaning.